Structural and mechanistic insights into the Rel protein of Mycobacterium tuberculosis

• Main Author: Singal, Bharti
• Other Authors: Gerhard Gruber
• Format: Thesis-Doctor of Philosophy
• Language: English
• Published: Nanyang Technological University 2020
• Subjects: Science::Biological sciences::Biochemistry; Science::Biological sciences::Biophysics; Science::Biological sciences::Microbiology::Bacteria
• Online Access: https://hdl.handle.net/10356/142669
• Institution: Nanyang Technological University

Mycobacterium tuberculosis (Mtb) is known to survive as slow-growing bacteria. However, under in-hostile conditions inside the human host, it can survive as persister. The persistent bacteria can stay dormant for months to years and hence doesn’t show any progression from latent infection to active...