Lipid accumulation facilitates mitotic slippage-induced adaptation to anti-mitotic drug treatment

• المؤلفون الرئيسيون: Wong, Alex, Chen, Sixun, Yang, Lay Kien, Kanagasundaram, Yoganathan, Crasta, Karen Carmelina
• مؤلفون آخرون: Interdisciplinary Graduate School (IGS)
• التنسيق: مقال
• اللغة: English
• منشور في: 2020
• الموضوعات: Science::Medicine; Lipid; Drug Treatment
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/143191
• المؤسسة: Nanyang Technological University

Aberrant lipid accumulation is a hallmark of cancer known to contribute to its aggressiveness and malignancy. Emerging studies have demonstrated context-dependent changes in lipid metabolism during chemotherapy. However, there is little known regarding the mechanisms linking lipid metabolism to chem...