Lipid accumulation facilitates mitotic slippage-induced adaptation to anti-mitotic drug treatment

• Main Authors: Wong, Alex, Chen, Sixun, Yang, Lay Kien, Kanagasundaram, Yoganathan, Crasta, Karen Carmelina
• Other Authors: Interdisciplinary Graduate School (IGS)
• Format: Article
• Language: English
• Published: 2020
• Subjects: Science::Medicine; Lipid; Drug Treatment
• Online Access: https://hdl.handle.net/10356/143191
• Institution: Nanyang Technological University

Aberrant lipid accumulation is a hallmark of cancer known to contribute to its aggressiveness and malignancy. Emerging studies have demonstrated context-dependent changes in lipid metabolism during chemotherapy. However, there is little known regarding the mechanisms linking lipid metabolism to chem...