Investigating ERO1α, IDO1 and MHC Class I : potential proteins that can be manipulated to change the tumour microenvironment from ‘cold’ to ‘hot’
ERO1α, a cancer-associated protein, and IDO1, an immunomodulatory enzyme, have been shown to be associated with the expression of MHC Class I proteins. Previous study done by our lab that showed ERO1α association with hypoxic tumour progression, also had preliminary data indicating that under hypoxi...
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Format: | Final Year Project |
Language: | English |
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Nanyang Technological University
2020
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Online Access: | https://hdl.handle.net/10356/143295 |
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Institution: | Nanyang Technological University |
Language: | English |