Localized delivery of CRISPR/dCas9 via layer-by-layer self-assembling peptide coating on nanofibers for neural tissue engineering

Localized delivery of CRISPR/dCas9 via layer-by-layer self-assembling peptide coating on nanofibers for neural tissue engineering

The clustered regularly interspaced short palindromic repeat (CRISPR) systems have a wide variety of applications besides precise genome editing. In particular, the CRISPR/dCas9 system can be used to control specific gene expression by CRISPR activation (CRISPRa) or interference (CRISPRi). However,...

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Bibliographic Details
Main Authors: Zhang, Kunyu, Chooi, Wai Hon, Liu, Shuang, Chin, Jiah Shin, Murray, Aoife, Nizetic, Dean, Cheng, Du, Chew, Sing Yian
Other Authors: School of Chemical and Biomedical Engineering
Format: Article
Language:English
Published: 2020
Subjects:
Engineering::Chemical engineering
Gene Delivery
CRISPR/Cas9
Online Access:https://hdl.handle.net/10356/143512
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Institution: Nanyang Technological University
Language: English

Internet

https://hdl.handle.net/10356/143512

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