Localized delivery of CRISPR/dCas9 via layer-by-layer self-assembling peptide coating on nanofibers for neural tissue engineering
The clustered regularly interspaced short palindromic repeat (CRISPR) systems have a wide variety of applications besides precise genome editing. In particular, the CRISPR/dCas9 system can be used to control specific gene expression by CRISPR activation (CRISPRa) or interference (CRISPRi). However,...
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Main Authors: | Zhang, Kunyu, Chooi, Wai Hon, Liu, Shuang, Chin, Jiah Shin, Murray, Aoife, Nizetic, Dean, Cheng, Du, Chew, Sing Yian |
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Other Authors: | School of Chemical and Biomedical Engineering |
Format: | Article |
Language: | English |
Published: |
2020
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/143512 |
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Institution: | Nanyang Technological University |
Language: | English |
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