Estrogen exacerbates mammary involution through neutrophil-dependent and -independent mechanism

• المؤلفون الرئيسيون: Lim, Chew Leng, Or, Yu Zuan, Ong, Zoe, Chung, Hwa Hwa, Hayashi, Hirohito, Shrestha, Smeeta, Chiba, Shunsuke, Lin, Feng, Lin, Valerie Chun Ling
• مؤلفون آخرون: School of Computer Science and Engineering
• التنسيق: مقال
• اللغة: English
• منشور في: 2020
• الموضوعات: Science; Developmental Biology; Estrogen
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/143516
• المؤسسة: Nanyang Technological University

There is strong evidence that the pro-inflammatory microenvironment during post-partum mammary involution promotes parity-associated breast cancer. Estrogen exposure during mammary involution drives tumor growth through neutrophils' activity. However, how estrogen and neutrophils influence mamm...