Estrogen exacerbates mammary involution through neutrophil-dependent and -independent mechanism

• Main Authors: Lim, Chew Leng, Or, Yu Zuan, Ong, Zoe, Chung, Hwa Hwa, Hayashi, Hirohito, Shrestha, Smeeta, Chiba, Shunsuke, Lin, Feng, Lin, Valerie Chun Ling
• 其他作者: School of Computer Science and Engineering
• 格式: Article
• 語言: English
• 出版: 2020
• 主題: Science; Developmental Biology; Estrogen
• 在線閱讀: https://hdl.handle.net/10356/143516
• 機構: Nanyang Technological University

There is strong evidence that the pro-inflammatory microenvironment during post-partum mammary involution promotes parity-associated breast cancer. Estrogen exposure during mammary involution drives tumor growth through neutrophils' activity. However, how estrogen and neutrophils influence mamm...