The human telomeric nucleosome displays distinct structural and dynamic properties

• المؤلفون الرئيسيون: Soman, Aghil, Liew, Chong Wai, Teo, Hsiang Ling, Berezhnoy, Nikolay V., Olieric, Vincent, Korolev, Nikolay, Rhodes, Daniela, Nordenskiöld, Lars
• مؤلفون آخرون: School of Chemical and Biomedical Engineering
• التنسيق: مقال
• اللغة: English
• منشور في: 2020
• الموضوعات: Science; Gene Regulation; Chromatin and Epigenetics
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/143977

Telomeres protect the ends of our chromosomes and are key to maintaining genomic integrity during cell division and differentiation. However, our knowledge of telomeric chromatin and nucleosome structure at the molecular level is limited. Here, we aimed to define the structure, dynamics as well as p...