The human telomeric nucleosome displays distinct structural and dynamic properties

• Main Authors: Soman, Aghil, Liew, Chong Wai, Teo, Hsiang Ling, Berezhnoy, Nikolay V., Olieric, Vincent, Korolev, Nikolay, Rhodes, Daniela, Nordenskiöld, Lars
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2020
• Subjects: Science; Gene Regulation; Chromatin and Epigenetics
• Online Access: https://hdl.handle.net/10356/143977
• Institution: Nanyang Technological University

Telomeres protect the ends of our chromosomes and are key to maintaining genomic integrity during cell division and differentiation. However, our knowledge of telomeric chromatin and nucleosome structure at the molecular level is limited. Here, we aimed to define the structure, dynamics as well as p...