Single-molecule compaction of megabase-long chromatin molecules by multivalent cations

Single-molecule compaction of megabase-long chromatin molecules by multivalent cations

To gain insight into the conformational properties and compaction of megabase-long chromatin molecules, we reconstituted chromatin from T4 phage DNA (165 kb) and recombinant human histone octamers (HO). The unimolecular compaction, induced by divalent Mg2+ or tetravalent spermine4+ cations, studied...

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Bibliographic Details
Main Authors: Zinchenko, Anatoly, Berezhnoy, Nikolay V., Wang, Sal, Rosencrans, William M., Korolev, Nikolay, van der Maarel, Johan R. C., Nordenskiöld, Lars
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2018
Subjects:
Gene Regulation
Chromatin
Online Access:https://hdl.handle.net/10356/89191
http://hdl.handle.net/10220/44813
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Institution: Nanyang Technological University
Language: English

Internet

https://hdl.handle.net/10356/89191
http://hdl.handle.net/10220/44813

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