Compaction and self-association of megabase-sized chromatin are induced by anionic protein crowding
Highly compacted chromatin, a complex of DNA with cationic histone proteins, is found in the nucleus of eukaryotic cells in an environment with a high concentration of macromolecular species, many of which possess a negative charge. In the majority of previous studies, however, these crowding condit...
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Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
2020
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/144055 |
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Institution: | Nanyang Technological University |
Language: | English |