Rapid, sensitive and highly specific label-free fluorescence biosensor for microRNA by branched rolling circle amplification

• المؤلفون الرئيسيون: Ma, Qian, Li, Pin, Gao, Zhiqiang, Li, Sam Fong Yau
• مؤلفون آخرون: Lee Kong Chian School of Medicine (LKCMedicine)
• التنسيق: مقال
• اللغة: English
• منشور في: 2020
• الموضوعات: Science::Medicine; MicroRNA; Terpyridine Zinc
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/144341
• المؤسسة: Nanyang Technological University

A simple fluorescence biosensor for rapid and sensitive target microRNA (miRNA) quantification by branched rolling circle amplification (BRCA) is developed in this work. Target miRNA functions as primer to recognize and hybridize with a circle DNA template, initiating rolling circle amplification (R...