65 years of the double helix : the advancements of gene editing and potential application to hereditary cancer
Hereditary cancer predisposition syndromes are associated with germline mutations that lead to increased vulnerability for an individual to develop cancers. Such germline mutations in tumour suppressor genes, oncogenes and genes encoding for proteins essential in DNA repair pathways and cell cycle c...
Saved in:
Main Authors: | Tan, Zi Ying, Huang, Taosheng, Ngeow, Joanne |
---|---|
Other Authors: | Lee Kong Chian School of Medicine (LKCMedicine) |
Format: | Article |
Language: | English |
Published: |
2020
|
Subjects: | |
Online Access: | https://hdl.handle.net/10356/144586 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Institution: | Nanyang Technological University |
Language: | English |
Similar Items
-
Sniper2L is a high-fidelity Cas9 variant with high activity
by: Kim, YH, et al.
Published: (2024) -
Crispr-cas9 mediated genome editing in bicyclus anynana butterflies
by: Banerjee, T.D., et al.
Published: (2021) -
DESIGN AND INVESTIGATION OF DUMBBELL-SHAPED DNA MINIMAL VECTORS FOR CRISPR/CAS9 EDITING
by: AVANTIKA GHOSH
Published: (2020) -
Localized delivery of CRISPR/dCas9 via layer-by-layer self-assembling peptide coating on nanofibers for neural tissue engineering
by: Zhang, Kunyu, et al.
Published: (2020) -
Structures of apo Cas12a and its complex with crRNA and DNA reveal the dynamics of ternary complex formation and target DNA cleavage
by: Jianwei, L, et al.
Published: (2023)