A laser microdissection-based axotomy model incorporating the use of biomimicking fiber scaffolds reveals microRNAs promote axon regeneration over long injury distances

• Main Authors: Zhang, Na, Lin, Junquan, Chin, Jiah Shin, Zhang, Kunyu, Chew, Sing Yian
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2020
• Subjects: Engineering::Chemical engineering; Nerve Tissue Engineering; Sciatic Nerve Injury
• Online Access: https://hdl.handle.net/10356/144907
• Institution: Nanyang Technological University

The regeneration of injured neurons over long injury distances remains suboptimal. In order to successfully stimulate nerve regrowth, potent biomolecules are necessary. Furthermore, reproducible and translatable methods to test the potency of candidate drugs in enhancing nerve regeneration over long...