Development of mucus-penetrating antibiotic and quorum sensing inhibitor nanoparticle complex for bronchiectasis therapy

• 主要作者: Tran, The Thien
• 其他作者: Kunn Hadinoto Ong
• 格式: Thesis-Doctor of Philosophy
• 語言: English
• 出版: Nanyang Technological University 2020
• 主題: Engineering::Chemical engineering::Biochemical engineering; Engineering::Nanotechnology
• 在線閱讀: https://hdl.handle.net/10356/145374

Bronchiectasis is a chronic respiratory disease characterized by permanent and irreversible dilatation of the airways caused by a vicious cycle of infection and inflammation, leading to the loss of lung function, morbidity, and mortality. Early results suggested inhaled ciprofloxacin (CIP) as a prom...