XGBoost improves classification of MGMT promoter methylation status in IDH1 wildtype glioblastoma

Approximately 96% of patients with glioblastomas (GBM) have IDH1 wildtype GBMs, characterized by extremely poor prognosis, partly due to resistance to standard temozolomide treatment. O6-Methylguanine-DNA methyltransferase (MGMT) promoter methylation status is a crucial prognostic biomarker for alky...

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Bibliographic Details
Main Authors: Le, Nguyen Quoc Khanh, Do, Duyen Thi, Chiu, Fang-Ying, Yapp, Edward Kien Yee, Yeh, Hui-Yuan, Chen, Cheng-Yu
Other Authors: School of Humanities
Format: Article
Language:English
Published: 2021
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Online Access:https://hdl.handle.net/10356/145898
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Institution: Nanyang Technological University
Language: English

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