Iridium-promoted deoxyglycoside synthesis : stereoselectivity and mechanistic insight

• المؤلفون الرئيسيون: Pal, Kumar Bhaskar, Guo, Aoxin, Das, Mrinmoy, Lee, Jiande, Báti, Gábor, Yip, Benjamin Rui Peng, Loh, Teck-Peng, Liu, Xue-Wei
• مؤلفون آخرون: School of Physical and Mathematical Sciences
• التنسيق: مقال
• اللغة: English
• منشور في: 2021
• الموضوعات: Science::Chemistry; Stereoselective O-glycosylation; Ir(I)-catalyst
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/147077
• المؤسسة: Nanyang Technological University

Herein, we devised a method for stereoselective O-glycosylation using an Ir(I)-catalyst which enables both hydroalkoxylation and nucleophilic substitution of glycals with varying substituents at the C3 position. In this transformation, 2-deoxy-α-O-glycosides were acquired when glycals equipped with...