Antibody neutralization of microbiota-derived circulating peptidoglycan dampens inflammation and ameliorates autoimmunity

The human microbiota provides tonic signals that calibrate the host immune response1,2, but their identity is unknown. Bacterial peptidoglycan (PGN) subunits are likely candidates since they are well-known immunity-enhancing adjuvants, released by most bacteria during growth, and have been found in...

Full description

Saved in:
Bibliographic Details
Main Authors: Huang, Zhenxing, Wang, Jianhe, Xu, Xiaoli, Wang, Haishan, Qiao, Yuan, Chu, Wern Cui, Xu, Shengli, Chai, Louis, Cottier, Fabien, Pavelka, Norman, Oosting, Marije, Joosten, Leo A. B., Netea, Mihai, Ng, Carol Yee Leng, Leong, Khai Pang, Kundu, Parag, Lam, Kong-Peng, Pettersson, Sven, Wang, Yue
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Article
Language:English
Published: 2021
Subjects:
Online Access:https://hdl.handle.net/10356/147107
Tags: Add Tag
No Tags, Be the first to tag this record!
Institution: Nanyang Technological University
Language: English