Structural and biochemical study of Candida albicans polarisomal proteins

• Main Author: Loh, Zhi Yang
• Other Authors: Gao Yonggui
• Format: Thesis-Doctor of Philosophy
• Language: English
• Published: Nanyang Technological University 2021
• Subjects: Science::Biological sciences::Biochemistry; Science::Biological sciences::Microbiology
• Online Access: https://hdl.handle.net/10356/147880
• Institution: Nanyang Technological University

The polarisome is a multi-protein complex involved in the assembly of actin cytoskeleton during polarised hyphae growth in pathogenic yeast C. albicans. In this thesis, we present the crystal structure of C. albicans polarisomal protein Aip5 (786-896) at 2.65 Å resolution. Structural comparison of n...