Folding kinetics of G-quadruplexes : duplex stem loops drive and accelerate G-quadruplex folding

• Main Authors: Nguyen, Thi Quynh Ngoc, Lim, Kah Wai, Phan, Anh Tuân
• Other Authors: School of Physical and Mathematical Sciences
• Format: Article
• Language: English
• Published: 2021
• Subjects: Science::Chemistry; Science::Biological sciences::Biophysics; Folding Kinetics; G-quadruplex
• Online Access: https://hdl.handle.net/10356/150057
• Institution: Nanyang Technological University

The folding kinetics is an important parameter affecting the relevance of DNA and RNA G-quadruplex (G4) structures in biological processes. Previous studies of the G4 folding kinetics mainly depended on fast measurement techniques. In previously available examples of G4s with loops up to three resid...