Regulation of T cell functions by an "ionic checkpoint"
This study advances the fundamental understandings of ionic-checkpoint and its role in regulating immune functions. Pharmacological activators are able to rescue T cells of the high K+-mediated suppression and restore T cell effector functions. Our study suggests a new approach for improving the ef...
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Format: | Student Research Poster |
Language: | English |
Published: |
Nanyang Technological University
2021
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Online Access: | https://hdl.handle.net/10356/151815 |
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Institution: | Nanyang Technological University |
Language: | English |
Summary: | This study advances the fundamental understandings of ionic-checkpoint and its role in regulating immune functions. Pharmacological activators are able to rescue T cells of the high K+-mediated suppression and restore T cell effector
functions. Our study suggests a new approach for improving the effectiveness of cancer immunotherapies. [1st Award] |
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