Regulation of T cell functions by an "ionic checkpoint"

This study advances the fundamental understandings of ionic-checkpoint and its role in regulating immune functions. Pharmacological activators are able to rescue T cells of the high K+-mediated suppression and restore T cell effector functions. Our study suggests a new approach for improving the ef...

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Main Author:	Ng, Aik Seng
Other Authors:	Chandy George Kanianthara
Format:	Student Research Poster
Language:	English
Published:	Nanyang Technological University 2021
Subjects:	Science::Biological sciences
Online Access:	https://hdl.handle.net/10356/151815
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Institution:	Nanyang Technological University
Language:	English

id	sg-ntu-dr.10356-151815
record_format	dspace
spelling	sg-ntu-dr.10356-1518152021-07-04T20:11:30Z Regulation of T cell functions by an "ionic checkpoint" Ng, Aik Seng Chandy George Kanianthara Navin Kumar Verma School of Biological Sciences nkverma@ntu.edu.sg, gchandy@ntu.edu.sg Science::Biological sciences This study advances the fundamental understandings of ionic-checkpoint and its role in regulating immune functions. Pharmacological activators are able to rescue T cells of the high K+-mediated suppression and restore T cell effector functions. Our study suggests a new approach for improving the effectiveness of cancer immunotherapies. [1st Award] 2021-07-02T05:21:22Z 2021-07-02T05:21:22Z 2019 Student Research Poster Ng, A. S. (2019). Regulation of T cell functions by an "ionic checkpoint". Student Research Poster, Nanyang Technological University, Singapore. https://hdl.handle.net/10356/151815 https://hdl.handle.net/10356/151815 en LKCM18005 © 2019 The Author(s). application/pdf Nanyang Technological University
institution	Nanyang Technological University
building	NTU Library
continent	Asia
country	Singapore Singapore
content_provider	NTU Library
collection	DR-NTU
language	English
topic	Science::Biological sciences
spellingShingle	Science::Biological sciences Ng, Aik Seng Regulation of T cell functions by an "ionic checkpoint"
description	This study advances the fundamental understandings of ionic-checkpoint and its role in regulating immune functions. Pharmacological activators are able to rescue T cells of the high K+-mediated suppression and restore T cell effector functions. Our study suggests a new approach for improving the effectiveness of cancer immunotherapies. [1st Award]
author2	Chandy George Kanianthara
author_facet	Chandy George Kanianthara Ng, Aik Seng
format	Student Research Poster
author	Ng, Aik Seng
author_sort	Ng, Aik Seng
title	Regulation of T cell functions by an "ionic checkpoint"
title_short	Regulation of T cell functions by an "ionic checkpoint"
title_full	Regulation of T cell functions by an "ionic checkpoint"
title_fullStr	Regulation of T cell functions by an "ionic checkpoint"
title_full_unstemmed	Regulation of T cell functions by an "ionic checkpoint"
title_sort	regulation of t cell functions by an "ionic checkpoint"
publisher	Nanyang Technological University
publishDate	2021
url	https://hdl.handle.net/10356/151815
_version_	1705151327874580480

Regulation of T cell functions by an "ionic checkpoint"

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