Endothelial glycocalyx degradation and disease severity in Plasmodium vivax and Plasmodium knowlesi malaria

• Main Authors: Barber, Bridget E., Grigg, Matthew J., Piera, Kim A., Chen, Youwei, William, Timothy, Weinberg, J. Brice, Yeo, Tsin Wen, Anstey, Nicholas M.
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2021
• Subjects: Science::Medicine; Biomarkers; Medical Research
• Online Access: https://hdl.handle.net/10356/151999
• Institution: Nanyang Technological University

Degradation of the endothelial glycocalyx is associated with mortality in adult falciparum malaria. However, its role in the pathogenesis of non-falciparum malaria is unknown. In Malaysian patients with knowlesi (n = 200) and vivax (n = 61) malaria, and in healthy controls (n = 50), we measured glyc...