Preparation and dynamic behavior of protein-polymer complexes formed with polymer-binding peptides

• Main Authors: Ravishankar, Samyukta, Suzuki, Seigo, Sawada, Toshiki, Lim, Sierin, Serizawa, Takeshi
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2021
• Subjects: Engineering::Chemical engineering; Ferritin; Protein-PNIPAM Complexes
• Online Access: https://hdl.handle.net/10356/152844
• Institution: Nanyang Technological University

The development of protein-polymer complexes using protein cages is garnering attention as a strategy to overcome challenges that relate to immunogenicity and protease degradation. We propose the use of thermoresponsive polymers such as poly(N-isopropylacrylamide) (PNIPAM) to form ferritin-polymer c...