Smart nanomicelles with bacterial infection-responsive disassembly for selective antimicrobial applications

• Main Authors: Pranantyo, Dicky, Kang, En-Tang, Chan-Park, Mary B.
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2021
• Subjects: Engineering::Chemical engineering::Polymers and polymer manufacture; Bacterial Metabolism; Biocompatible Polymer
• Online Access: https://hdl.handle.net/10356/154042
• Institution: Nanyang Technological University

New generation antimicrobial agents are expected to exhibit non-metabolic killing mechanisms, high killing potency and biocompatibility. We synthesized a cationic chitosan derivative and an anionic chitosan derivative – specifically an α-poly(L)lysine side-grafted chitosan (CS-PLL) and an anionic ci...