Towards understanding the mode of action of the cytotoxic triosmium carbonyl cluster Os₃(CO)₁₀(NCCH₃)₂ : Its reactivity with amino acids and oligopeptides

• المؤلفون الرئيسيون: Lee J.J.Y., Leong W.K.
• مؤلفون آخرون: School of Physical and Mathematical Sciences
• التنسيق: مقال
• اللغة: English
• منشور في: 2021
• الموضوعات: Science::Chemistry; Osmium; Carbonyl Cluster
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/154584

The reactions of the triosmium carbonyl cluster Os₃(CO)₁₀(NCCH₃)₂ (1) with a number of protected amino acids, tri- and pentapeptides were examined. The results show that reaction with the side chains follow the order: -SH > -COOH > -CONH₂, and there is a slight preference for the longer side c...