Use of a benzyl ether as a traceless hydrogen donor in the anti-Markovnikov hydrofunctionalization of alkenes with xanthates

• المؤلفون الرئيسيون: Hayashi, Hirohito, Kaga, Atsushi, Wang, Bin, Gagosz, Fabien, Chiba, Shunsuke
• مؤلفون آخرون: School of Physical and Mathematical Sciences
• التنسيق: مقال
• اللغة: English
• منشور في: 2022
• الموضوعات: Science::Chemistry; Alkene Derivative; Benzyl Derivative
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/154849
• المؤسسة: Nanyang Technological University

A new protocol for the anti-Markovnikov hydrofunctionalization of alkenyl alcohol O-Bn ethers was developed using xanthates as functionalizing agents in the presence of lauroyl peroxide as a radical initiator and a stoichiometric oxidant. The benzyl group serves as a traceless hydrogen donor in the...