C2 amination of pyridine with primary amines mediated by sodium hydride in the presence of lithium iodide

• المؤلفون الرئيسيون: Pang, Jia Hao, Ong, Derek Yiren, Chiba, Shunsuke
• مؤلفون آخرون: School of Physical and Mathematical Sciences
• التنسيق: مقال
• اللغة: English
• منشور في: 2022
• الموضوعات: Science::Chemistry; Acridine Derivative; Benzyl Cyanide
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/154826
• المؤسسة: Nanyang Technological University

N-Butylpyridin-2-amine (3). An oven-dried, 250 mL three-necked roundbottomed flask fitted with a 25 x 15 mm Teflon-coated oval magnetic stir bar, a thermometer, rubber septum and a Liebig reflux condenser, is connected to a Schlenk line (Note 2). Sodium hydride (NaH) (3.00 g, 75.0 mmol, 3.0 equiv)...