Cleavage and reassembly C≡C bonds of ynones to access highly functionalized ketones

• المؤلفون الرئيسيون: Rong, Jiaxin, Li, Haowen, Fu, Rui, Sun, Wangbin, Loh, Teck-Peng, Jiang, Yaojia
• مؤلفون آخرون: School of Physical and Mathematical Sciences
• التنسيق: مقال
• اللغة: English
• منشور في: 2022
• الموضوعات: Science::Biological sciences::Biochemistry; Ynones; Carbenes
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/155163
• المؤسسة: Nanyang Technological University

An economical strategy has been designed to formally cleave CC bonds of ynones through copper-catalyzed carbene chemistry. It proceeds under mild reaction conditions in a step-economy process by simultaneously cleaving the CC bonds and constructing C-C bonds. Depending on the substitution of the yno...