Facile access to chiral ketones through metal-free oxidative C-C bond cleavage of aldehydes by O2

• المؤلفون الرئيسيون: Tiwari, Bhoopendra, Zhang, Junming, Chi, Robin Yonggui
• مؤلفون آخرون: School of Physical and Mathematical Sciences
• التنسيق: مقال
• اللغة: English
• منشور في: 2012
• الموضوعات: DRNTU::Engineering::Chemical engineering::Biochemical engineering
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/94646; http://hdl.handle.net/10220/8117
• المؤسسة: Nanyang Technological University

Giving the metal the boot: The title reaction provides facile access to functionalized chiral ketones from chiral α,α′-disubstituted aldehydes in the presence of molecular oxygen (see scheme). The CC bond-cleavage approach offers an alternative or better method relative to the typical bond-forming s...