Facile access to chiral ketones through metal-free oxidative C-C bond cleavage of aldehydes by O2

Giving the metal the boot: The title reaction provides facile access to functionalized chiral ketones from chiral α,α′-disubstituted aldehydes in the presence of molecular oxygen (see scheme). The CC bond-cleavage approach offers an alternative or better method relative to the typical bond-forming s...

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Main Authors: Tiwari, Bhoopendra, Zhang, Junming, Chi, Robin Yonggui
Other Authors: School of Physical and Mathematical Sciences
Format: Article
Language:English
Published: 2012
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Online Access:https://hdl.handle.net/10356/94646
http://hdl.handle.net/10220/8117
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Institution: Nanyang Technological University
Language: English
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spelling sg-ntu-dr.10356-946462020-03-07T12:31:30Z Facile access to chiral ketones through metal-free oxidative C-C bond cleavage of aldehydes by O2 Tiwari, Bhoopendra Zhang, Junming Chi, Robin Yonggui School of Physical and Mathematical Sciences DRNTU::Engineering::Chemical engineering::Biochemical engineering Giving the metal the boot: The title reaction provides facile access to functionalized chiral ketones from chiral α,α′-disubstituted aldehydes in the presence of molecular oxygen (see scheme). The CC bond-cleavage approach offers an alternative or better method relative to the typical bond-forming strategies used in synthesizing chiral ketones. 2012-05-22T09:02:46Z 2019-12-06T18:59:36Z 2012-05-22T09:02:46Z 2019-12-06T18:59:36Z 2012 2012 Journal Article Tiwari, B., Zhang, J. & Chi, R. Y. (2012). Facile Access to Chiral Ketones through Metal-Free Oxidative CC Bond Cleavage of Aldehydes by O2. Angewandte Chemie International Edition, 51(8), 1911-1914. https://hdl.handle.net/10356/94646 http://hdl.handle.net/10220/8117 10.1002/anie.201107473 165026 en Angewandte chemie international edition © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
institution Nanyang Technological University
building NTU Library
country Singapore
collection DR-NTU
language English
topic DRNTU::Engineering::Chemical engineering::Biochemical engineering
spellingShingle DRNTU::Engineering::Chemical engineering::Biochemical engineering
Tiwari, Bhoopendra
Zhang, Junming
Chi, Robin Yonggui
Facile access to chiral ketones through metal-free oxidative C-C bond cleavage of aldehydes by O2
description Giving the metal the boot: The title reaction provides facile access to functionalized chiral ketones from chiral α,α′-disubstituted aldehydes in the presence of molecular oxygen (see scheme). The CC bond-cleavage approach offers an alternative or better method relative to the typical bond-forming strategies used in synthesizing chiral ketones.
author2 School of Physical and Mathematical Sciences
author_facet School of Physical and Mathematical Sciences
Tiwari, Bhoopendra
Zhang, Junming
Chi, Robin Yonggui
format Article
author Tiwari, Bhoopendra
Zhang, Junming
Chi, Robin Yonggui
author_sort Tiwari, Bhoopendra
title Facile access to chiral ketones through metal-free oxidative C-C bond cleavage of aldehydes by O2
title_short Facile access to chiral ketones through metal-free oxidative C-C bond cleavage of aldehydes by O2
title_full Facile access to chiral ketones through metal-free oxidative C-C bond cleavage of aldehydes by O2
title_fullStr Facile access to chiral ketones through metal-free oxidative C-C bond cleavage of aldehydes by O2
title_full_unstemmed Facile access to chiral ketones through metal-free oxidative C-C bond cleavage of aldehydes by O2
title_sort facile access to chiral ketones through metal-free oxidative c-c bond cleavage of aldehydes by o2
publishDate 2012
url https://hdl.handle.net/10356/94646
http://hdl.handle.net/10220/8117
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