Investigating non-nucleoside inhibitors targeting the Zika virus non-structural protein 5 (NS5) RNA-dependent RNA polymerase (RdRp) domain

• Main Author: Zhang, Denzel Xugeng
• Other Authors: Julien Lescar
• Format: Final Year Project
• Language: English
• Published: Nanyang Technological University 2022
• Subjects: Science::Biological sciences
• Online Access: https://hdl.handle.net/10356/157309
• Institution: Nanyang Technological University

Zika virus and members of the Flaviviridae family are re-emerging pathogens that pose a significant threat to public health. The lack of a vaccine and specific treatment of has resulted in a need for the design of therapeutic treatments to target specific parts of virus replication cycles. H...