INPP5K and Atlastin-1 maintain the nonuniform distribution of ER-plasma membrane contacts in neurons

• Main Authors: Sun, Jingbo, Harion, Raihanah, Naito, Tomoki, Saheki, Yasunori
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2022
• Subjects: Science::Medicine; Cell Membrane; Animals
• Online Access: https://hdl.handle.net/10356/159287
• Institution: Nanyang Technological University

In neurons, the ER extends throughout all cellular processes, forming multiple contacts with the plasma membrane (PM) to fine-tune neuronal physiology. However, the mechanisms that regulate the distribution of neuronal ER-PM contacts are not known. Here, we used the Caenorhabditis elegans DA9 motor...