Antiviral activity against Middle East Respiratory Syndrome coronavirus by Montelukast, an anti-asthma drug

• Main Authors: Gan, Hanjie Jonathan, Harikishore, Amaravadhi, Lee, Jihye, Jeon, Sangeun, Rajan, Sreekanth, Chen, Ming Wei, Neo, Jun Long, Kim, Seungtaek, Yoon, Ho Sup
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2022
• Subjects: Science::Biological sciences; MERS-CoV; Receptor-Binding Domain
• Online Access: https://hdl.handle.net/10356/159916
• Institution: Nanyang Technological University

Middle East Respiratory Syndrome (MERS) is a respiratory disease caused by a coronavirus (MERS-CoV). Since its emergence in 2012, nosocomial amplifications have led to its high epidemic potential and mortality rate of 34.5%. To date, there is an unmet need for vaccines and specific therapeutics for...