A 3D physio-mimetic interpenetrating network-based platform to decode the pro and anti-tumorigenic properties of cancer-associated fibroblasts

• Main Authors: Cao, Huan, Cheng, Hong Sheng, Wang, Jun Kit, Tan, Nguan Soon, Tay, Chor Yong
• Other Authors: School of Materials Science and Engineering
• Format: Article
• Language: English
• Published: 2022
• Subjects: Engineering::Materials; Interpenetrating Network Hydrogel; Cancer-Associated Fibroblasts
• Online Access: https://hdl.handle.net/10356/160210
• Institution: Nanyang Technological University

Three-dimensional (3D) biomaterials with physiologically relevant and experimentally tractable biomechanical features are important platforms to advance our understanding of the influence of tissue mechanics in disease progression. Herein, an interpenetrating network (IPN) of collagen and alginate 3...