Recent advances in investigating functional dynamics of chromatin

• المؤلفون الرئيسيون: Shi, Xiangyan, Zhai, Ziwei, Chen, Yinglu, Li, Jindi, Nordenskiöld, Lars
• مؤلفون آخرون: School of Biological Sciences
• التنسيق: مقال
• اللغة: English
• منشور في: 2022
• الموضوعات: Science::Biological sciences; Nuclear Magnetic Resonance; Molecular Dynamics Simulations
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/160255
• المؤسسة: Nanyang Technological University

Dynamics spanning the picosecond-minute time domain and the atomic-subcellular spatial window have been observed for chromatin in vitro and in vivo. The condensed organization of chromatin in eukaryotic cells prevents regulatory factors from accessing genomic DNA, which requires dynamic stabilizatio...