Positive cooperativity in the activation of E. coli aquaporin Z by cardiolipin: potential for lipid-based aquaporin modulators
Aquaporins (AQPs) are tetrameric integral membrane proteins (IMPs) that permeabilize cellular membranes to water [1]. Their architecture is well conserved from bacteria to humans [2] where each monomer (~ 25 kDa) acts as a water channel [3]. Although AQPs in humans regulate water transport in sev...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
2022
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10356/160421 |
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| Institution: | Nanyang Technological University |
| Language: | English |