Proteomic analysis of human liver cell line incubated with s-enantiomer of warfarin

• المؤلف الرئيسي: Tay, Jacqueline Mei Shi.
• مؤلفون آخرون: Chen Wei Ning, William
• التنسيق: Final Year Project
• اللغة: English
• منشور في: 2009
• الموضوعات: DRNTU::Engineering::Chemical engineering::Biochemical engineering
• الوصول للمادة أونلاين: http://hdl.handle.net/10356/16141

Warfarin acts as a specific inhibitor of vitamin K epoxide reductase, with S-enantiomer being more active than R-enantiomer. It is clinically used as oral anti-coagulant to effectively treat patients with pulmonary embolism. To achieve an optimal therapeutic response with minimum side effects, quant...