Molecular basis of accessible plasma membrane cholesterol recognition by the GRAM domain of GRAMD1b
Cholesterol is essential for cell physiology. Transport of the "accessible" pool of cholesterol from the plasma membrane (PM) to the endoplasmic reticulum (ER) by ER-localized GRAMD1 proteins (GRAMD1a/1b/1c) contributes to cholesterol homeostasis. However, how cells detect accessible chole...
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Main Authors: | Ercan, Bilge, Naito, Tomoki, Koh, Dylan Hong Zheng, Dharmawan, Dennis, Saheki, Yasunori |
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Other Authors: | Lee Kong Chian School of Medicine (LKCMedicine) |
Format: | Article |
Language: | English |
Published: |
2022
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/161493 |
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Institution: | Nanyang Technological University |
Language: | English |
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