Molecular basis of accessible plasma membrane cholesterol recognition by the GRAM domain of GRAMD1b

Cholesterol is essential for cell physiology. Transport of the "accessible" pool of cholesterol from the plasma membrane (PM) to the endoplasmic reticulum (ER) by ER-localized GRAMD1 proteins (GRAMD1a/1b/1c) contributes to cholesterol homeostasis. However, how cells detect accessible chole...

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Bibliographic Details
Main Authors: Ercan, Bilge, Naito, Tomoki, Koh, Dylan Hong Zheng, Dharmawan, Dennis, Saheki, Yasunori
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Article
Language:English
Published: 2022
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Online Access:https://hdl.handle.net/10356/161493
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Institution: Nanyang Technological University
Language: English

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