Profiling the 'deamidome' of complex biosamples using mixed-mode chromatography-coupled tandem mass spectrometry

Deamidation is a spontaneous degenerative protein modification (DPM) that disrupts the structure and function of both endogenous proteins and various therapeutic agents. While deamidation has long been recognized as a critical event in human aging and multiple degenerative diseases, research progres...

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Main Authors: Sze, Siu Kwan, JebaMercy, Gnanasekaran, Ngan, SoFong Cam
其他作者: School of Biological Sciences
格式: Article
語言:English
出版: 2022
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在線閱讀:https://hdl.handle.net/10356/161729
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機構: Nanyang Technological University
語言: English