Precise chemodynamic therapy of cancer by trifunctional bacterium-based nanozymes

• Main Authors: Zhang, Weiyun, Liu, Jiawei, Li, Xuyu, Zheng, Yue, Chen, Lianfu, Wang, Dongdong, Foda, Mohamed Frahat, Ma, Zhaoyu, Zhao, Yanli, Han, Heyou
• Other Authors: School of Physical and Mathematical Sciences
• Format: Article
• Language: English
• Published: 2022
• Subjects: Science::Chemistry; Ferroptosis; Immunotherapy
• Online Access: https://hdl.handle.net/10356/162056
• Institution: Nanyang Technological University

Chemodynamic therapy (CDT) destroys cancer cells by converting H2O2 or O2 into reactive oxygen species (ROS), but its therapeutic efficacy is restricted by the antioxidant capacity of tumor. Previous solutions focused on strengthening the nanodrugs with the ability to increase ROS production or weak...