Observations that suggest a contribution of altered dermal papilla mitochondrial function to androgenetic alopecia

• المؤلفون الرئيسيون: Chew, Elaine Guo Yan, Lim, Tze Chiun, Leong, Meng Fatt, Liu, Xingliang, Sia, Yee Yen, Leong, See Ting, Yan-Jiang, Benjamin C., Stoecklin, Celine, Borhan, Rosa, Heilmann-Heimbach, Stefanie, Nöthen, Markus M., Viasnoff, Virgile, Ng, Shyh-Chang, Wan, Andrew C. A., Philpott, Michael P., Hillmer, Axel M.
• مؤلفون آخرون: Lee Kong Chian School of Medicine (LKCMedicine)
• التنسيق: مقال
• اللغة: English
• منشور في: 2022
• الموضوعات: Science::Medicine; Androgens; Co-Culture Techniques
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/162702

Androgenetic alopecia (AGA) is a prevalent hair loss condition in males that develops due to the influence of androgens and genetic predisposition. With the aim of elucidating genes involved in AGA pathogenesis, we modelled AGA with three-dimensional culture of keratinocyte-surrounded dermal papilla...