Vascular dysfunction in malaria: understanding the role of the endothelial glycocalyx

• Main Authors: Bush, Margaret A., Anstey, Nicholas M., Yeo, Tsin Wen, Florence, Salvatore M., Granger, Donald L., Mwaikambo, Esther D., Weinberg, J. Brice
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2022
• Subjects: Science::Medicine; Glycocalyx; Malaria
• Online Access: https://hdl.handle.net/10356/163183
• Institution: Nanyang Technological University

Malaria caused by Plasmodium falciparum results in over 400,000 deaths annually, predominantly affecting African children. In addition, non-falciparum species including vivax and knowlesi cause significant morbidity and mortality. Vascular dysfunction is a key feature in malaria pathogenesis leading...