Study of Ube3a knockdown and expression in the in vitro system.

• المؤلف الرئيسي: Ng, Xiang Wen.
• مؤلفون آخرون: Chen Ken-Shiung
• التنسيق: Final Year Project
• اللغة: English
• منشور في: 2009
• الموضوعات: DRNTU::Science::Biological sciences::Molecular biology
• الوصول للمادة أونلاين: http://hdl.handle.net/10356/16321
• المؤسسة: Nanyang Technological University

Angelman syndrome (AS) is a neurological disorder which is caused by loss of maternally expressed genes on the human chromosome 15q11-q13 in the brain. AS patients show signs of mental retardation, seizures, lack of speech and ataxic gait. In this study, we would like to look into Ube3a, whose mutat...