BF₃-promoted reactions of α-amino acetals with alkynes to 2,5-disubstituted pyrroles
An efficient BF₃-promoted cyclization of α-amino acetals with alkynes for the assembly of substituted pyrroles has been developed. This cascade process uses easily accessible α-amino acetals as raw materials and can be achieved under mild conditions through a simple metal-free operation.
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| Main Authors: | , , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | English |
| Published: |
2022
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10356/163494 |
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| Institution: | Nanyang Technological University |
| Language: | English |
| Summary: | An efficient BF₃-promoted cyclization of α-amino acetals with alkynes for the assembly of substituted pyrroles has been developed. This cascade process uses easily accessible α-amino acetals as raw materials and can be achieved under mild conditions through a simple metal-free operation. |
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