BF₃-promoted reactions of α-amino acetals with alkynes to 2,5-disubstituted pyrroles

An efficient BF₃-promoted cyclization of α-amino acetals with alkynes for the assembly of substituted pyrroles has been developed. This cascade process uses easily accessible α-amino acetals as raw materials and can be achieved under mild conditions through a simple metal-free operation.

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Bibliographic Details
Main Authors: Gao, Zhi-Yuan, He, Yu, Li, Lan-Yang, Tian, Jie-Sheng, Loh, Teck-Peng
Other Authors: School of Physical and Mathematical Sciences
Format: Article
Language:English
Published: 2022
Subjects:
Online Access:https://hdl.handle.net/10356/163494
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Institution: Nanyang Technological University
Language: English

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