Neuronal IRE-1 coordinates an organism-wide cold stress response by regulating fat metabolism
Cold affects many aspects of biology, medicine, agriculture, and industry. Here, we identify a conserved endoplasmic reticulum (ER) stress response, distinct from the canonical unfolded protein response, that maintains lipid homeostasis during extreme cold. We establish that the ER stress sensor IRE...
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Main Authors: | Dudkevich, Reut, Koh, Jhee Hong, Beaudoin-Chabot, Caroline, Celik, Cenk, Lebenthal-Loinger, Ilana, Karako-Lampert, Sarit, Syed Ahmad-Albukhari, Thibault, Guillaume, Henis-Korenblit, Sivan |
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Other Authors: | School of Biological Sciences |
Format: | Article |
Language: | English |
Published: |
2023
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/164688 |
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Institution: | Nanyang Technological University |
Language: | English |
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