Malaria parasite stress tolerance is regulated by DNMT2-mediated tRNA cytosine methylation

• Main Authors: Hammam, Elie, Sinha, Ameya, Baumgarten, Sebastian, Nardella, Flore, Liang, Jiaqi, Miled, Samia, Bonhomme, Frédéric, Erdmann, Diane, Arcangioli, Benoit, Arimondo, Paola B., Dedon, Peter, Preiser, Peter, Scherf, Artur
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2023
• Subjects: Science::Biological sciences; Malaria; Epitranscriptomic
• Online Access: https://hdl.handle.net/10356/165029
• Institution: Nanyang Technological University

Malaria parasites need to cope with changing environmental conditions that require strong countermeasures to ensure pathogen survival in the human and mosquito hosts. The molecular mechanisms that protect Plasmodium falciparum homeostasis during the complex life cycle remain unknown. Here, we identi...