Adipose-specific PPARα knockout mice have increased lipogenesis by PASK-SREBP1 signaling and a polarity shift to inflammatory macrophages in white adipose tissue

Adipose-specific PPARα knockout mice have increased lipogenesis by PASK-SREBP1 signaling and a polarity shift to inflammatory macrophages in white adipose tissue

The nuclear receptor PPARα is associated with reducing adiposity, especially in the liver, where it transactivates genes for β-oxidation. Contrarily, the function of PPARα in extrahepatic tissues is less known. Therefore, we established the first adipose-specific PPARα knockout (PparaFatKO) mice to...

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書目詳細資料
Main Authors:	Hinds, Terry D., Kipp, Zachary A., Xu, Mei, Yiannikouris, Frederique B., Morris, Andrew J., Stec, Donald F., Wahli, Walter, Stec, David E.
其他作者:	Lee Kong Chian School of Medicine (LKCMedicine)
格式:	Article
語言:	English
出版:	2023
主題:	Science::Medicine Obesity Cholesterol Esters
在線閱讀:	https://hdl.handle.net/10356/165261
標簽:	添加標簽沒有標簽, 成為第一個標記此記錄!
機構:	Nanyang Technological University
語言:	English

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