Mechanisms of telomere regulation: characterizing TRF1-mediated phase separation of nucleosomes

Telomeres are functionally conserved regions at the ends of chromosomes that confer protection. The dysregulation of telomeres has been implicated in diseases of aging and cancer, but not all underlying mechanisms of telomere regulation have been fully elucidated. Recently, liquid-liquid phase separ...

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Bibliographic Details
Main Author: Ng, Brendan Wei-Jie
Other Authors: Lars Nordenskiöld
Format: Final Year Project
Language:English
Published: Nanyang Technological University 2023
Subjects:
Online Access:https://hdl.handle.net/10356/166549
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Institution: Nanyang Technological University
Language: English